Zilbrysq (zilucoplan)
Filled with a prescription and delivered free to your door, with help on prior authorization.
Zilbrysq is a medicine called a complement inhibitor. It is a lab-made peptide (a short chain of amino acids, the building blocks of proteins) that blocks a protein called C5, which is part of the immune system's complement system.
MedRx Infusion can fill Zilbrysq with a prescription and deliver it free to your door.
What Zilbrysq is prescribed for
- Generalized myasthenia gravis: adults with generalized myasthenia gravis (an immune disease that causes muscle weakness) who test positive for anti-acetylcholine receptor (AChR) antibodies.
A prescription is required. Your prescriber decides whether Zilbrysq is right for you.
How Zilbrysq is given
Injection under the skin, given by you or a caregiver, after training. A nurse can show you or a caregiver how to give it.
Storage: Keep it in the refrigerator (36°F to 46°F) in its original carton to protect it from light, and do not freeze it. You may keep it at room temperature (up to 86°F) in the carton for one period of up to 3 months (write the date on the carton), but do not put it back in the refrigerator after that.
Before you start
Before the first dose, your prescriber may ask for:
- meningococcal vaccines (shots against meningococcal bacteria, groups A, C, W, Y and B) at least 2 weeks before the first dose; if treatment must start sooner, you get antibiotics and the vaccines as soon as possible
- vaccines against pneumococcus (bacteria that can cause pneumonia and other serious infections)
- a blood test of two pancreas enzymes (lipase and amylase)
- your prescriber must be enrolled in a restricted program (the Zilbrysq REMS), and you will get a wallet card (the Patient Safety Card) to carry with you at all times during treatment and for 2 months after it ends
Important safety information: This medicine has a boxed warning about serious, life-threatening meningococcal infections (infections of the blood or the lining of the brain). Because of this risk, it is only available through a restricted program called the Zilbrysq REMS.
Zilbrysq is available only through the Zilbrysq REMS, a safety program the FDA requires. MedRx Infusion is certified to dispense it.
Read the Medication Guide and the full Zilbrysq prescribing information, and ask your prescriber or our pharmacists about side effects. Our pharmacists are on call 24 hours a day.
Insurance and prior authorization
Health plans often require prior authorization for Zilbrysq. Our intake team checks your coverage and works with your prescriber’s office on the paperwork before your first delivery.
The manufacturer runs a support program, ONWARD, that may help eligible patients with costs and access.
How to refer a patient
Offices can call (844) 671-2600 or fax a referral to (844) 671-2601. Use the Neurology Referral Form (PDF).
The manufacturer also publishes Zilbrysq ONWARD Start Form and enrollment.
Questions
01Does MedRx Infusion fill Zilbrysq?
Yes. MedRx Infusion can fill Zilbrysq with a prescription and deliver it free to your door. Our intake team confirms access and coverage for each patient.
02What is Zilbrysq used for?
Zilbrysq is approved for generalized myasthenia gravis. Your prescriber decides whether it is right for you.
03Can Zilbrysq be given at home?
Yes. You or a caregiver can give Zilbrysq at home after training, and a nurse can show you how. Your prescriber decides which form is right for you.
04Does insurance cover Zilbrysq?
Coverage depends on your health plan, and many plans require prior authorization. Our intake team checks your coverage before your first delivery.
Key facts
- Organization
- MedRx Infusion Clinical Pharmacy
- What we do
- A home infusion pharmacy and specialty pharmacy, with infusion nurses who visit patients at home and a pharmacist on call 24 hours a day, 7 days a week.
- Where
- Pharmacy at 417 N Oak St, Inglewood, CA 90302. Licensed in 43 states, the District of Columbia and Puerto Rico. See every place we serve
- Accreditation
- URAC (Specialty Pharmacy) and ACHC (Accreditation Commission for Health Care).
- Phone, 24 hours
- (844) 671-2600
- Fax
- (844) 671-2601
Accurate as of
Send a referral
Intake handles benefits investigation, prior authorization and scheduling.
Send a referralFax
(844) 671-2601
Send a completed referral form