Xolair (omalizumab)

• Allergic asthma: adults and children 6 years and older with moderate to severe persistent asthma who have a positive skin or blood test to an allergen in the air all year round, and whose symptoms are not well controlled with inhaled steroids (inhaled corticosteroids); not for sudden breathing problems.
• Chronic rhinosinusitis with nasal polyps (CRSwNP): adults 18 years and older with nasal polyps (growths in the nose and sinuses) that did not respond well enough to steroid nose sprays; used as an add-on maintenance treatment (taken along with your other daily medicines).
• IgE-mediated food allergy: adults and children 1 year and older with IgE-mediated food allergy, to lower allergic reactions, including anaphylaxis, that may happen after accidental contact with one or more foods; used along with avoiding those foods, and not for emergency treatment of a reaction.
• Chronic spontaneous urticaria (CSU): adults and children 12 years and older with chronic spontaneous urticaria (long-lasting hives with no known cause) who still have symptoms while taking H1 antihistamines (allergy pills); not for other kinds of hives.

A prescription is required. Your prescriber decides whether Xolair is right for you.

Injection under the skin, given by a healthcare professional, or you or a caregiver after training.

The label says treatment starts in a healthcare setting. After at least three doses without a serious allergic reaction, your prescriber may let you or a caregiver give the shots at home after training, and a nurse can show you how.

Storage: Keep prefilled syringes and autoinjectors in the refrigerator in the original carton, away from direct sunlight, and do not freeze them. They can be out of the refrigerator for no more than 2 days in total.

Before the first dose, your prescriber may ask for:

• a blood test for total IgE (an allergy antibody), except for chronic hives
• a check of your body weight, except for chronic hives

Important safety information: This medicine has a boxed warning about anaphylaxis (a sudden, severe allergic reaction that can be life-threatening), which can happen after any dose, even the first. Treatment starts in a healthcare setting, where you are watched for a while after each shot.

Read the Medication Guide and the full Xolair prescribing information, and ask your prescriber or our pharmacists about side effects. Our pharmacists are on call 24 hours a day.

Health plans often require prior authorization for Xolair. Our intake team checks your coverage and works with your prescriber’s office on the paperwork before your first delivery.

The manufacturer runs a support program, Xolair Co-pay Program, that may help eligible patients with costs and access.

Offices can call (844) 671-2600 or fax a referral to (844) 671-2601. Use the Allergy and Asthma Referral Form (PDF).

The manufacturer also publishes Xolair Access Solutions forms (Prescriber Service Form and Patient Consent Form).