Remicade (infliximab)

• Crohn's disease: adults and children 6 years and older with moderately to severely active Crohn's disease (swelling and sores in the gut) when usual treatments did not work well enough. Zymfentra is only for adults, to keep treating Crohn's disease after starting infliximab by IV.
• Crohn's disease with fistulas: adults with Crohn's disease that has formed draining fistulas (abnormal tunnels from the bowel to the skin or vagina).
• Ulcerative colitis: adults and children 6 years and older with moderately to severely active ulcerative colitis (swelling and sores in the large bowel) when usual treatments did not work well enough. Zymfentra is only for adults, to keep treating ulcerative colitis after starting infliximab by IV.
• Rheumatoid arthritis: adults with moderately to severely active rheumatoid arthritis (a disease where the immune system attacks the joints), used together with methotrexate.
• Ankylosing spondylitis: adults with active ankylosing spondylitis (arthritis that mainly affects the spine).
• Psoriatic arthritis: adults with psoriatic arthritis (joint pain and swelling linked to psoriasis).
• Plaque psoriasis: adults with chronic severe plaque psoriasis (a skin condition with thick, scaly patches) who could use medicine that treats the whole body (systemic therapy), when other systemic treatments are less suitable.

A prescription is required. Your prescriber decides whether Remicade is right for you.

IV infusion, given by a healthcare professional. When your prescriber agrees it can be given at home, we send a skilled nurse from an accredited nursing agency to give it.

Injection under the skin, given by you or a caregiver, after training. A nurse can show you or a caregiver how to give it.

Storage: Remicade, Inflectra, Avsola and Renflexis are stored and mixed by your care team. Keep Zymfentra pens and syringes in the refrigerator in the original carton to protect them from light, and do not freeze them; if you keep one at room temperature (up to 14 days), do not put it back in the refrigerator.

Before the first dose, your prescriber may ask for:

• a test for tuberculosis (TB)
• a blood test for hepatitis B
• a check that your vaccines are up to date

Important safety information: This medicine has a boxed warning about the risk of serious infections, including tuberculosis (TB), and certain cancers, such as lymphoma (cancer of the lymph system).

Read the Medication Guide and the full Remicade prescribing information, and ask your prescriber or our pharmacists about side effects. Our pharmacists are on call 24 hours a day.

Health plans often require prior authorization for Remicade. Our intake team checks your coverage and works with your prescriber’s office on the paperwork before your first delivery.

The manufacturer runs a support program, J&J withMe, that may help eligible patients with costs and access.

Offices can call (844) 671-2600 or fax a referral to (844) 671-2601. Use the Rheumatology Referral Form (PDF).

The manufacturer also publishes Remicade benefit investigation and enrollment forms.