Dupixent (dupilumab)

• Atopic dermatitis (eczema): adults and children 6 months and older with moderate to severe atopic dermatitis (eczema) that is not well controlled with prescription skin treatments, or when those treatments are not a good choice.
• Asthma: adults and children 6 years and older with moderate to severe asthma that is the eosinophilic type (linked to high levels of a white blood cell called eosinophils) or that needs steroid pills (oral corticosteroids); used as an add-on maintenance treatment (taken along with your other daily medicines), not for sudden breathing problems.
• Chronic rhinosinusitis with nasal polyps (CRSwNP): adults and children 12 years and older with long-lasting swelling of the nose and sinuses with growths called nasal polyps that is not well controlled; used as an add-on maintenance treatment.
• Eosinophilic esophagitis (EoE): adults and children 1 year and older who weigh at least 15 kg (about 33 pounds) with eosinophilic esophagitis (swelling of the food pipe caused by eosinophils, a type of white blood cell).
• Prurigo nodularis: adults with prurigo nodularis (a skin condition with hard, very itchy bumps).
• COPD: adults with chronic obstructive pulmonary disease (COPD, a long-term lung disease) that is not well controlled and is the eosinophilic type; used as an add-on maintenance treatment, not for sudden breathing problems.
• Chronic spontaneous urticaria (CSU): adults and children 2 years and older with chronic spontaneous urticaria (long-lasting hives with no known cause) who still have symptoms while taking H1 antihistamines (allergy pills); not for other kinds of hives.
• Bullous pemphigoid: adults with bullous pemphigoid (a skin condition that causes large, itchy blisters).
• Allergic fungal rhinosinusitis (AFRS): adults and children 6 years and older with allergic fungal rhinosinusitis (an allergic reaction to fungus in the sinuses) who have had sinus surgery before.

A prescription is required. Your prescriber decides whether Dupixent is right for you.

Injection under the skin, given by you or a caregiver, after training. A nurse can show you or a caregiver how to give it.

Storage: Keep it in the refrigerator in its original carton to protect it from light. If needed, it can stay at room temperature (up to 77°F) for up to 14 days; do not freeze it, shake it or let it get hot.

Before the first dose, your prescriber may ask for:

• a check that your vaccines are up to date, so you can get any you need first
• treatment first of any worm (helminth) infection you already have

Read the Medication Guide and the full Dupixent prescribing information, and ask your prescriber or our pharmacists about side effects. Our pharmacists are on call 24 hours a day.

Health plans often require prior authorization for Dupixent. Our intake team checks your coverage and works with your prescriber’s office on the paperwork before your first delivery.

The manufacturer runs a support program, Dupixent MyWay, that may help eligible patients with costs and access.

Offices can call (844) 671-2600 or fax a referral to (844) 671-2601. Use the Dermatology Referral Form (PDF).

The manufacturer also publishes Dupixent MyWay enrollment forms.