Briumvi (ublituximab-xiiy)

• Relapsing forms of multiple sclerosis (MS): adults with relapsing forms of multiple sclerosis (a disease where the immune system attacks the covering of nerves in the brain and spinal cord). This includes clinically isolated syndrome (a first episode of MS-like symptoms), relapsing-remitting MS (flare-ups followed by periods of recovery) and active secondary progressive MS (MS that slowly gets worse but still has flare-ups).

A prescription is required. Your prescriber decides whether Briumvi is right for you.

IV infusion, given by a healthcare professional.

The label calls for close supervision by an experienced healthcare professional, medicine beforehand to lower the risk of infusion reactions, and at least an hour of observation after the first two infusions. Your prescriber decides where you get it. When it can be given at home, we send a skilled nurse from an accredited nursing agency.

Before the first dose, your prescriber may ask for:

• a blood test for hepatitis B
• a blood test of your immunoglobulin (antibody) levels
• blood tests of your liver
• a review of your vaccines, because some vaccines need to be given weeks before you start
• a check for any active infection

Read the Medication Guide and the full Briumvi prescribing information, and ask your prescriber or our pharmacists about side effects. Our pharmacists are on call 24 hours a day.

Health plans often require prior authorization for Briumvi. Our intake team checks your coverage and works with your prescriber’s office on the paperwork before your first delivery.

The manufacturer runs a support program, Briumvi Patient Support, that may help eligible patients with costs and access.

Offices can call (844) 671-2600 or fax a referral to (844) 671-2601. Use the Multiple Sclerosis Referral Form (PDF).

The manufacturer also publishes Briumvi Start Form and getting started.