Botox (onabotulinumtoxinA)

• Overactive bladder (OAB): adults with OAB (leaking urine, a strong and sudden need to go, and going often) when an anticholinergic medicine did not work well enough or could not be taken.
• Bladder leaks from a nerve condition: adults who leak urine because the bladder muscle is overactive due to a nerve condition, such as a spinal cord injury or multiple sclerosis (MS), when an anticholinergic medicine did not work well enough or could not be taken.
• Neurogenic detrusor overactivity (NDO) in children: children 5 years and older whose bladder muscle is overactive because of a nerve condition, when an anticholinergic medicine did not work well enough or could not be taken.
• Chronic migraine: adults with chronic migraine (headache on 15 or more days a month, lasting 4 hours a day or longer), to prevent headaches. It is not for episodic migraine (14 or fewer headache days a month).
• Spasticity: people 2 years and older with spasticity (stiff, tight muscles).
• Cervical dystonia: adults with cervical dystonia (neck muscles tighten on their own, causing an abnormal head position and neck pain), to reduce how severe these are.
• Severe underarm sweating: adults with severe underarm sweating with no other cause (primary axillary hyperhidrosis) that is not managed well enough with products put on the skin.
• Blepharospasm: people 12 years and older with blepharospasm (eyelids squeeze shut on their own) linked to dystonia.
• Strabismus: people 12 years and older with strabismus (eyes that do not line up).

A prescription is required. Your prescriber decides whether Botox is right for you.

Injection into a muscle, given by a healthcare professional.

Botox is injected by a doctor trained in these injections, usually in the office or clinic. Ask your doctor how you will get it.

Before the first dose, your prescriber may ask for:

• a check for infection where the shots will go
• for bladder treatment, a check that you do not have a urinary tract infection (UTI)
• for bladder treatment, a check that you can empty your bladder, or that you are able to use a catheter if needed
• for underarm sweating, a check for other causes of heavy sweating, such as an overactive thyroid (hyperthyroidism)

Important safety information: This medicine has a boxed warning about the toxin spreading beyond the injection site. This can cause muscle weakness, vision problems, and trouble swallowing or breathing, which can be life-threatening, from hours to weeks after the shot.

Read the Medication Guide and the full Botox prescribing information, and ask your prescriber or our pharmacists about side effects. Our pharmacists are on call 24 hours a day.

Health plans often require prior authorization for Botox. Our intake team checks your coverage and works with your prescriber’s office on the paperwork before your first delivery.

The manufacturer runs a support program, BOTOX Complete Savings Program, that may help eligible patients with costs and access.

Offices can call (844) 671-2600 or fax a referral to (844) 671-2601. Use the Neurology Referral Form (PDF).

The manufacturer also publishes BOTOX ONE patient access and support, including BOTOX Complete enrollment.